Aging Brain

As global populations age, the incidence of seizures and epilepsy rises sharply—particularly after age 65. Yet the mechanisms that make the aging brain more vulnerable to abnormal electrical activity remain poorly understood. A growing body of evidence points toward dysfunction in one crucial system: the neurovascular unit (NVU).

Aging was once considered inevitable—a slow, quiet drift toward biological decline.But over the last decade, scientists have discovered something extraordinary: Aging is not just about time . It’s also about the accumulation of a specific type of damaged cell that refuses to die. These cells—called senescent cells —build up in the body as we age. They don’t divide, they don’t function normally, and they secrete toxic molecules that damage surrounding tissues. They accelerate

By understanding - and modifying - the biology of aging, we have the chance to: ✔ prevent disease before it starts✔ slow or reverse early damage✔ develop therapies that work across conditions✔ extend cognitive healthspan, not just lifespan✔ rethink dementia as something we can influence, not simply endure.

Aging doesn’t cause neurodegeneration in a direct, linear way. Rather, it gradually weakens the systems that normally protect the brain.